“ Her medical history was unremarkable except for complications following an appendectomy three years prior which resulted in a deep vein thrombosis ( DVT) and subsequent pulmonary embolism. Comparative studies with different AChEIs did not show any significant difference or traces of superiority among them in AD patients ( Wilkinson et al 2002 ; Ritchie et al 2004 ; Aguglia et al 2004 ; Bullock et al 2005 ; Harry and Zakzanis 2005). If contraception fails, termination of pregnancy (an abortion) may be advised if pregnancy arises during treatment with isotretinoin or within a month of discontinuing it. But the trauma of a common severe withdrawal reaction will give you stress on a level you didnt realize was humanly possible to experience…. The risk or severity of adverse effects can be increased when Clomipramine is combined with Chlorprothixene. Use only the smallest amount needed to get relief from your pain, swelling, or fever. ”